(Mechanics of Biological and Soft Materials)
Bin Chen, Zhejiang University
Baohua Ji, Beijing Institute of Technology
Symposium Technical Description
Cell mechanics plays central roles in understanding how cell actively senses and responds to physical cues including force, geometry, dimension and matrix elasticity, which is of significance in various biological processes, as well as in human pathology. One prominent trend of cell mechanics is to investigate hierarchal structures and nested processes occurring at multiple time scales and length scales, which brings unprecedented challenges and great opportunities to both experimentalists and theoreticians. Here we propose the following four themes:
Molecular Biomechanics: Protein interaction, DNA mechanics, protein-DNA interaction, Kinetics of molecular motors, Mechanosensitive ion channels, etc.
Cellular or sub-cellular Mechanics: Cell-matrix interaction, Cytoskeleton dynamics, Cell motility, Cell division, Mechanics of endocytosis or exocytosis, Membrane, Nuclear mechanics, sub-cellular structures and organelles, etc.
Mechanics of extracellular matrix and tissue mechanics: Mechanical properties of soft or hard tissues, Tissue engineering, Tissue morphogenesis, Mechanics of biopolymers, Interfaces or surface properties of extracellular matrix, etc.
Novel techniques and tools: Molecular biosensors, Traction force spectroscopy, Tweezers, AFM, FRET, Pillar arrays, Super-resolution imaging, 3D printing, etc.
Monday | M1 10:00am-11:40am
|C10-1: Multiscale Studies of Cell Mechanics|
|2111||Session Chair: Bin Chen, Baohua Ji||Track C: Mechanics of Biological and Soft Materials|
|10:00 am||Relaxing cells by light (Invited)
|10:20 am||Mean deformation metrics for quantifying 3D cell-matrix interactions (Invited)
Eyal Bar-Kochba, Jonathan Estrada, Jennet Toyjanova, Haneesh Kesari, Jonathan S. Reichner, Christian Franck
|10:40 am||Mechanics of collective cell polarization and arrangement on patterned substrate (Invited)
|11:00 am||The quest for the determination of the gaussian modulus—exploiting membrane edge fluctuations
Metthew Zelisko, Huajian Gao, Pradeep Sharma
|11:20 am||Thermodynamics of mechanotransduction at intercellular junctions